Palliative Care Clinical Trials

Our team is dedicated to clinical research in the field of palliative care. For more information on any of these trials, or to find out if you're eligible to participate, contact Carolyn Revta, Palliative Care Clinical Research Operations Director, crevta@ucsd.edu or 858-822-3614.

Ongoing Studies

Positive Support in Cancer Care: Emphasizing Quality of Life and Legacy

Status: Currently recruiting
Eligible: Cancer patients who are eligible for or are currently receiving hospice or palliative care
This study focuses on the positive outcomes of providing cancer patients with extra support and attention. Patients included in this study will receive extra support from trained clinicians over the course of approximately two weeks. There will be two groups in the study. One group will be focused on support through storytelling and the creation of a life story (legacy) document. The second group will be focused on general support for daily needs or concerns. The primary goal of this study will help researchers understand the impact of different types of psychosocial support and how this process may positively impact people's well-being and quality of life.

SWOG S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride

Status: Currently recruiting
ClinicalTrials.gov identifier: NCT01416688
Eligible: Patients with a diagnosis of colorectal or lung cancer planning to receive HER1/EGFR therapy
There are a group of drugs called EGFR inhibitors (cetuximab, panitumumab and erlotinib) that often cause rash and other skin problems. Doctors and nurses need to record how severe they are in order to know whether to lower the dose. Doctors and nurses use a widely accepted grading tool that describes signs and symptoms associated with the rash and assigns a number to the rash in order of severity to evaluate the rash. However, descriptions in the grading tool do not always match what the doctors and nurses see in their examinations. A new questionnaire (FACT-EGFR 18) was developed to allow patients to rate, from their point of view, how severe their skin toxicities are and how these symptoms affect their quality of life. The questionnaire has to be used by several patients who are being treated with these drugs in order to show that the questionnaire can measure skin symptoms in a reliable manner. The purpose of this study is to have patients on these kinds of drugs who experience skin side effects when taking EGFR inhibitors, provide information about their skin symptoms through the FACT-EGFR 18 questionnaire, to see if it can be used as a reliable tool along with the usual grading tool to better manage side effects caused by these drugs. Eligible patients include those diagnosed with colorectal or lung cancers planning to receive certain HER/EGFR inhibitor therapies for at least 6 weeks. During this study, patients will be asked to fill out questionnaires rating the extent to which the patient experiences skin related side effects. These questionnaires will be completed weekly for 6 weeks and then monthly for 3 months. Participation in this trial will not prohibit participation in other clinical trials at Moores Cancer Center.


Contact

Carolyn Revta
Palliative Care Clinical Research Operations Director
Moores Cancer Center
crevta@ucsd.edu
Phone: 858-822-3614