Selected Publications

Sargent NSE, Price JE, Darling DL, Flynn MP, Tarin D.  Effects of altering surface glycoprotein composition on metastatic colonisation potential of murine mammary tumour cells. Br J Cancer 55:21‑28, 1987

Juacaba SF, McKinnell RG, Hanson WJ, Tarin D. Vascular dissemination of tumor cells in relation to temperature‑dependent metastasis in frogs. J Natn Cancer Inst 78:259‑264, 1987

Clarke PJ, Tarin D.  Effect of pre‑operative blood transfusion on tumour metastases.  Br J Surg 74:520‑522, 1987

Wallace JS, Fleming KA, Tarin D.  Tumourigenic transformation of mouse NIH 3T3 cells by transfection with plasmid pSV2neo. J Pathol 156:73‑76, 1988

McMenamin MM, Hayle AJ, Darling DL, Whittaker PA, Tutty MB, Clarke PJ, Tarin D.  Genetic basis of metastasis.  Adv Exp Biol Med 233:269‑279, 1988

Price JE, Tarin D, Fidler IJ.  The influence of organ microenvironment on pigmentation of a metastatic murine melanoma. Cancer Res 48:2258‑2264, 1988

Tarin D.  Molecular genetics of metastasis. In: Ciba Foundation Symposium on Metastasis. eds: Whelan J, Bock G R: John Wiley & Sons Ltd, London, 1988, pp. 149‑169

Tarin D. Interactions between genetic constitution of metastatic tumour cells and host factors. In: Tumor Progression and Metastasis.  eds: Nicolson G L, Fidler I J: Alan R. Liss Inc. New York, 1988, vol. 78,  pp. 157‑159

Juacaba SF, Horak E, Price JE, Tarin D.  Tumour cell dissemination patterns and metastasis of murine mammary carcinoma.  Cancer Res 49:570‑575, 1989

Price JE, Tarin D.  Low incidence of tumourigenicity in agarose colonies from spontaneous murine mammary tumours. Differentiation 41:202‑207, 1989               

Wallace J S, Hayle AJ, Syms AJ, Cairney M, Tutty  MB, Gazzard A, Evans MF, Fleming KA, Tarin D.  The ras oncogene and tumour metastasis: Observations on murine tumour cells transfected with the activated human c‑Harvey ras gene.  Differentiation 41:208‑215, 1989

Darling D, Tarin D.  The spread of cancer in the human body.  New Scientist 1726:50‑53, 1990

Tarin D. Tumour metastasis.  In: Oxford Textbook of Pathology. eds: McGee J O'D, Wright NA, Isaacson P G: Oxford University Press, Oxford, 1992,  pp. 607‑633

Moffett BF, Baban DF, Bao L, Tarin D.  Fate of clonal lineages during neoplasia and metastasis studied with an incorporated genetic marker.  Cancer Res 52:1737‑1743, 1992

Matsumura Y, Tarin D.  DNA fingerprinting survey of various human tumors and their metastases.  Cancer Res 52:2174‑2179, 1992

Matsumura Y, Tarin DSignificance of CD44 gene products for cancer diagnosis and disease evaluation.  Lancet 340:1053‑1058, 1992

Tarin D, Matsumura Y.  CD44 and cancer ‑ reply. Lancet 341:252‑253, 1993

Baban D, Matsumura Y, Kocialkowski S, Tarin D.  Studies on relationships between metastatic and non‑metastatic tumour cell populations using lineages labeled with dominant selectable genetic markers.  Int J Devel Biol 37:237‑243, 1993

Bao L, Pigott R, Matsumura Y, Baban D, Tarin D.  Correlation of VLA‑4 integrin expression with metastatic potential in various human tumour cell lines.  Differentiation 52:239‑246, 1993

Hayle AJ, Darling DL, Taylor AR, Tarin D.   Transfection of metastatic capability with total genomic DNA from human and mouse metastatic tumour cell lines.  Differentiation 54:177‑189, 1993

Tarin D, Matsumura Y.  Deranged CD44 gene activity in malignancy. J Pathol 171:249‑250, 1993

Matsumura Y, Tarin D.   Deranged activity of the CD44 gene and other loci as biomarkers for progression to metastatic malignancy.  J Cell Biochem: 17G:173‑185, 1993

Matsumura Y, Hanbury D, Smith JC, Tarin D.  Non‑invasive detection of malignancy by identification of unusual CD44 gene activity associated with exfoliated cancer cells.  Br Med J 308:619‑624, 1994

Tarin D, Matsumura Y.  Recent advances in the study of tumour invasion and metastasis. J Clin Pathol 47:385‑390, 1994

Bao L, Matsumura Y, Baban D, Sun Y, Tarin D.  Effects of inoculation site and Matrigel on growth and metastasis of  human breast cancer cells.  Br J Cancer 70:228‑232, 1994

Quinn JMW, Matsumura Y, Tarin D, McGee JO'D, Athanasou NA.   Cellular and hormonal mechanisms associated with malignant bone resorption. Lab Invest 71:465‑471, 1994

Tarin D.  Cancer Metastasis  In: Oxford Textbook of Oncology eds: Peckham M, Pinedo B, Veronesi U: Oxford University Press, Oxford 1995 pp.118‑132

Sugiyama M, Woodman A, Sugino T, Crowley S, Ho K, Smith H, Matsumura Y, Tarin D. Non‑invasive detection of bladder cancer by identification of abnormal CD44 proteins in exfoliated cancer cells in urine.  J Clin Pathol-Mol Pathol 48:M142‑M147, 1995

Matsumura Y, Sugiyama M, Matsumura S, Hayle AJ, Robinson P, Smith JC, Tarin D.  Unusual retention of introns in CD44 gene transcripts in bladder cancer provides new diagnostic and clinical oncological opportunities.  J Pathol 177:11‑20, 1995

Borgya A, Woodman A, Sugiyama M, Donie F, Kopetski E, Matsumura Y, Tarin D.  Isolation and characterisation of antibodies which specifically recognize the peptide encoded by exon 7 (V2) of the human CD44 gene.  J Clin Pathol-Mol Pathol 48:M241‑M250, 1995

Yoshida K, Bolodeoku J, Sugino T, Goodison S, Matsumura Y, Warren BF, Toge T, Tahara E, Tarin D.  Abnormal retention of intron 9 in CD44 gene transcripts in human gastrointestinal tumors.  Cancer Res 55: 4273‑4277, 1995

Tarin D.  Tumour Metastasis: Secondary proliferation of tumour cells in distant organs.   In: Cell Proliferation in Cancer eds: Pusztai, L, Lewis CE,Yap E.  Oxford University Press, Oxford, 1996,  pp. 316‑341.

Tarin D, Bolodeoku J, Hatfill SJ, Sugino T, Woodman A C, Yoshida K The clinical significance of malfunction of the CD44 locus in malignancy.  J Neuro‑Oncol 26:209‑219, 1995

Bolodeoku J, Yoshida K, Yeomans P, Wells CA, Tarin D. Demonstration of CD44 gene expression in cells from fine needle aspirates of breast lesions by the polymerase chain reaction.   J Clin Pathol-Mol Pathol 48:M307‑M309, 1995

Yoshida K, Sugino T, Bolodeoku J, Warren BF, Goodison S, Woodman A, Toge T, Tahara E, Tarin D.  Detection of exfoliated carcinoma cells in colonic luminal washings by identification of deranged patterns of expression of the CD44 gene. J Clin Pathol 49:300‑305, 1996

Gorham H, Sugino T, Woodman AC, Tarin D.  Cellular distribution of CD44 gene transcripts in colorectal carcinomas and in normal colonic mucosa. J Clin Pathol 49:482‑488, 1996

Higashikawa K, Yokozaki Y, Ue T, Taniyama K, Ishikawa T, Tarin D,  Tahara E. Evaluation of CD44 transcription variants in human digestive tract carcinomas and normal tissues.  Int J Cancer  66:11‑17, 1996

Gorham H, Sugino T, Bolodeoku J, Yoshida K, Goodison S, Tarin D.  Distribution of CD44 messenger RNA in archival paraffin wax embedded tumours and normal tissues viewed by in situ hybridisation.  J Clin Pathol-Mol Pathol 49:M147‑M150, 1996

Sugino T, Yoshida K, Bolodeoku J, Tahara H, Buley I, Manek S, Wells C, Goodison S, Ide T, Suzuki T, Tahara E, Tarin D.  Telomerase activity in human breast cancer and benign breast lesions: Diagnostic applications in clinical specimens including fine needle aspirates.  Int J Cancer (Pred Oncol): 69:301‑306, 1996

Yoshida K, Goodison S, Sugino T, Bolodeoku J, Churchman M, Warren BF, Tarin D.  Semiquantitative detection of abnormal CD44 transcripts in colon carcinomas by reverse transcription‑polymerase chain reaction enzyme‑linked immunosorbant assay (RT‑PCR ELISA) Mol Diag 1:167‑173, 1996

Sugino T, Gorham H, Yoshida K, Bolodeoku J, Nargund V, Cranston D, Goodison S, Tarin D.  Progressive loss of CD44 gene expression in invasive bladder cancer.  Am J Pathol 149:873‑882, 1996

Bolodeoku J, Yoshida K, Sugino T, Goodison S, Tarin D.  Accumulation of immature intron‑containing CD44 gene transcripts in breast cancer tissues.  Mol Diag 1:175‑181, 1996

Tarin D.  Diagnosis and prognostic assessment of gastrointestinal cancer by analysis of anomalous CD44 gene expression.  In: Recent Advances in Gastroenterological Carcinogenesis I. eds: Tahara E, Sugimachi K, Oohara T: Monduzzi Editore, Italy, 1996,  pp. 271‑274

Goodison S, Yoshida K, Tarin D.  CD44 intron retention in colonic tumour tissues.  In: Recent Advances in Gastroenterological Carcinogenesis I.  eds: Tahara E, Sugimachi K, Oohara T: Monduzzi Editore, Italy, 1996, pp. 977‑982 

Woodman AC, Sugiyama M, Yoshida K, Borgya A, Goodison S, Matsumura Y, Tarin D. Analysis of anomalous CD44 gene expression in human breast, bladder and colon cancer and correlation of observed mRNA and protein isoforms.  Am J Pathol 149:1519‑1530, 1996

Yoshida K, Sugino T, Tahara H, Woodman A, Bolodeoku J, Nargund V, Fellows G, Goodison S, Tahara E, Tarin D.  Telomerase activity in bladder carcinoma and its implication for non‑invasive diagnosis by detection of exfoliated cancer cells in urine. Cancer 79:362‑369, 1997

Tarin D.  Prognostic markers and mechanisms of metastasis.   In: Recent Advances in Histopathology 17 eds: Anthony PP. MacSween RNM, Lowe D: Churchill Livingstone, Edinburgh, 1997: pp. 15‑45 

Yoshida K, Sugino T, Goodison S, Warren BF, Nolan D, Wadsworth S, Mortensen NJ, Toge T, Tahara E, Tarin D.  Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications.  Br J Cancer 75:548‑553, 1997

Tarin D. Abnormal CD44 gene expression in neoplasia: Biological and clinical implications.  In: Molecular Pathology of Gastroenterological Cancer: Application to Clinical Practice.  ed: Tahara E: Springer‑Verlag, Tokyo, 1996, pp. 171-187

Tarin D.  Strategies to identify metastasis‑related genes.  In: Pathology Update/The Metastatic Process, Vol 4 ed: Nesland JM: Gustav Fischer Verlag, Stuttgart, 1996, pp.151-159

Sugino T, Yoshida K, Bolodeoku J, Tarin D, Goodison S.  Telomerase activity and its inhibition in benign and malignant breast lesions.  J Pathology 183:57-61, 1997

Gorham H, Yoshida K, Sugino T, Charnock M, Tarin D, Goodison, S.  Telomerase activity in human gynaecological tissues.  J Clin Path 50(6):501-504, 1997

Goodison S, Yoshida K, Sugino T, Woodman A, Gorham H, Bolodeoku J, Kaufman M, Tarin D.  Rapid analysis of distinctive CD44 RNA splicing preferences that characterize colonic tumors.  Cancer Res 57:3140-3144, 1997

Bolodeoku J, Yoshida K, Sugino T, Churchman M, Goodison, S, Tarin D. CD44 variant gene transcripts in human breast carcinomas. Biochem. Soc. Trans. Vol 25, No. 2, 356-357      (1997).

Goodison S and Tarin D.  The current status of CD44 variant isoforms as cancer diagnostic markers.  Histopathology 32:1-6, 1998

Sugino T, Yoshida K, Zhao S, Goodison S and Tarin D.  Disorderly CD44 gene expression in human cancer cells can be modulated by growth conditions. J of Pathology 186:17-23 (1998).

Goodison, S, Yoshida K, Churchman M, Sugino T and Tarin D: Multiple intron retention occurs in tumor cell CD44 mRNA processing.  Am J Pathology 153:1221-8 (1998).

Aogi K, Kitihara K, Buley I, Backdahl M, Tahara H, Sugino T, Tarin D, and Goodison S: Telomerase activity in lesions of the thyroid: Application to diagnosis of clinical samples including fine needle aspirates.  Clinical Cancer Res 4: 1965-1970, 1998.

Tokue Y, Matsumara N, Katsumata T, Watanabe D, Tarin D and Kakizoe T:  CD44 variant isoform expression and breast cancer prognosis.  Japan J Cancer Res 89:283-290, 1998.

Goodison S and Tarin D:   Clinical implications of anomalous CD44 gene expression in neoplasia.  Frontiers in Bioscience 3:89-109, 1998.

Urquidi V, Tarin D and Goodison S: Telomerase in Cancer: Clinical Applications. Annals of Med 30: 419-430, 1998.

Gorham H, Woodman A, Yoshida K, Marsh J, Manek S, Sugino T,  Charnock M,  Goodison S and Tarin D:CD44  expression in  cervical intraepithelial neoplasia (CIN) and carcinoma. Mol Diag 4: 45-57, 1999.

Goodison S, Urquidi V, Tarin D.  CD44 cell adhesion molecules. J Clin Pathol: Mol Pathol 52: 1999.

Urquidi V, Tarin D, Goodison S.  Role of Telomerase in Cell Senscence and Oncogenesis. Commissioned review – Annual  Rev of Med 2000.

Aogi K, Kitihara K, Urquidi V, Tarin D, Goodison S.  Comparison of CD44 Isoforms and telomerase activity diagnostic tumor marker. Clinical Cancer Research 5: 2790-2797, 1999.

Woodman AC, Goodison S, Drake M, Noble J, Tarin D.  Non-Invasive Diagnosis of Bladder Carcinoma by ELISA Detection of CD44 Isoforms in Exfoliated Urothelia.  Clinical Cancer Research, Vol. 6, 2381-2392,  2000.

Urquidi V, Tarin D, Goodison S.  Role of Telomerase in Cell Senescence and Oncogenesis.  Ann. Rev. Med.  51: 65-79, 2000.

Aogi K, Woodman A, Urquidi V, Mangham D, Tarin D, and Goodison S.  Telomerase Activity in Soft-Tissue and Bone Sarcomas.  Clinical Cancer Research 6: 4776-4781, 2000.

Montel V, Kleeman J, Agarwal D, Spinella D, Kawai K, Tarin D. Altered Metastatic Behavior of Human Breast Cancer Cells after Experimental Manipulation of Matrix Metalloproteinase 8 Gene Expression. Cancer Res. 64, 1687-1694, 2004

Suzuki M, Mose ES, Galloy C and Tarin D. Osteopontin Gene Expression Determines Spontaneous Metastatic Performance Of Orthotopic Human Breast Cancer Xenografts. Am J Path 171, 682-692, 2007

Tarin D, Price JE, Kettlewell MGW, Souter RG, Vass ACR, Crossley B. Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts. Cancer Res 44:3584 3592, 1984

Suzuki M, and Tarin D. Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: Clinical implications Molecular Oncology 1, 172-180, 2007