Research & Training

Publications

Partial list of publications incorporating use of this resource since 2001:

  1. Vigneri P and JYJ Wang. (2001). Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nature Med. 7: 228-234.
  2. Borsig L, Wong R, Feramisco JR, Nadeau D, Varki N, and Varki A. Platelets, P-selectin, heparin and cancer metastasis: new mechanistic connections with therapeutic potential. PNAS 98:3352-3357, 2001.
  3. Crawford BE, Olson SK, Pinhal MAS, and Esko JD. (2001) Cloning, Golgi localization, and enzyme activity of the full length heparin/heparan sulfate:glucuronic acid C5 epimerase. J. Biol. Chem. 76:21538-21543.
  4. Miller Y, Chang M, Funk C, Feramisco J and Witztum J. 12/15-Lipoxygenase translocation enhances site-specific actin polymerization in macrophages phagocytosing apoptotic cells. JBC 276:19431-39, 2001.
  5. Bai X, Zhou D, Brown JR, Hennet T. and Esko JD. (2001) Biosynthesis of the linkage region of glycosaminoglycans: Cloning and activity of Galactosyltransferase II, the sixth member of the__1,3galactosyltransferase family (_3GalT6), JBC 276:48189-95.
  6. Frasca F, Vigneri P, Vella V, Vigneri R and Wang JYJ (2001). Tyrosine kinase inhibitor STI571 enhances the motile response of thyroid cancer cells to hepatocyte growth factor. Oncogene. 20:3845-3856.
  7. Puri P, Iezzi S, Stiegler P, Chen T, Schiltz R, Muscat G, Giordano A, Kedes L, Wang JYJ, and Sartorelli V (2001). Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis. Mol. Cell. 8: 885-897.
  8. Srinivasan S, Rashka KE, Bier E. Creation of a Sog morphogen gradient in the Drosophila embryo. Dev Cell. 2002; 2:91-101. (Cover)
  9. Sobko A, Ma H, Firtel RA. Regulated SUMOylation and ubiquitination of DdMEK1 is required for proper chemotaxis. Dev Cell. 2002; 2:745-56. (Cover)
  10. Tsukada N, Burger JA, Zvaifler NJ, Kipps TJ. Distinctive features of "nurselike" cells that differentiate in the context of CLL. Blood. 2002; 99:1030-7. (Cover)
  11. Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell. 2002;110:55-67.
  12. Gudi T, Chen JC, Casteel DE, Seasholtz TM, Boss GR, Pilz RB cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions. J Biol Chem. 2002; 277:37382-93.
  13. Park JM, Greten FR, Li ZW, Karin M. Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science. 2002; 297:2048-51.
  14. Sutterlin C, Hsu P, Mallabiabarrena A, Malhotra V. Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells. Cell. 2002; 109:359-69.
  15. Worrall DS and Olefsky JM. (2002) The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes. Mol. Endo. 16:378-389.
  16. Taupenot L, Harper KL, Mahapatra NR, Parmer RJ, Mahata SK, O'Connor DT. Identification of a novel sorting determinant for the regulated pathway in the secretory protein chromogranin A. 2002; J Cell Science 155:4827-4841.
  17. Hazra PP, Suriapranata I, Snyder WB, Subramani S. Peroxisome remnants in pex3delta cells and the requirement of Pex3p for interactions between the peroxisomal docking and translocation subcomplexes. Traffic. 2002; 3:560-74.
  18. Kioussi C, Briata P, Baek S-H, Rose DW, Hamblet NS, Herman T, Lin C, Gleiberman A, Wang J, Ruiz-Lozano P, Szeto D, Wang D, Glass CK, Gleiberman A, Wang J, Brault V, Ruiz-Lozano P, Nguyen HD, Kemmler R, Glass CK, Wynshaw-Boris A, and Rosenfeld MG. Identification of a Wnt/Dvl/b-catenin ® Pitx2 Pathway Mediating Cell Type-Specific Proliferation during Development. Cell 111:673-85 (2002).
  19. Putkey FR, Cramer T, Mayhew MK, Silk AD, Johnson RS, McIntosh JR and Cleveland DW. (2002); Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev. Cell:3, 351-365.
  20. Puri PL, Bhakta K, Wood LD, Costanzo A, Zhu J, and Wang JYJ (2002). A myogenic differentiation checkpoint activated by genotoxic stress. Nature Genet. 32(4):585-93
  21. Lunyak VV, Burgess R. Prefontaine GG, Nelson C, Sze S-H, Chenoweth J, Pevzner PA, Schwartz P, Glass CK, Mandel G, and Rosenfeld MG. Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes. Science 298(5599):1747-52 (2002).
  22. Guibinga GH, Miyanohara A, Esko JD and Friedmann T. Cell surface heparan sulfate is a receptor for attachment of envelope protein-free retrovirus-like particles (VLP) and VSV-G pseudotyped MLV-derived retrovirus vectors to target cells. Molec.Ther.5:538-546 (2002).
  23. Trama J, Go WY, Ho SN. The osmoprotective function of the NFAT5 transcription factor in T cell development and activation. J Immunol. 2002; 169:5477-88.
  24. Miller YI, Worrall DS, Funk CD, Feramisco JR, Witztum JL. Actin polymerization in macrophages in response to oxidized LDL and apoptotic cells: role of 12/15-lipoxygenase and phosphoinositide 3-kinase. Mol Biol Cell. 2003 Oct;14(10):4196-206
  25. Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells. J Biol Chem. 2003 Jan 17;278(3):1561-8.
  26. Weaver B, Putkey F and Cleveland D (2003). CENP-E is essential for the mammalian spindle assembly checkpoint to prevent single chromosome loss. JCB 162, 551-563.
  27. Goodyear CS and Silverman GJ. Death by a B Cell Superantigen: In Vivo VH-targeted Apoptotic Supraclonal B Cell Deletion by a Staphylococcal Toxin. J Exp Med 197(9), 1125-39. 2003.
  28. Sundarrajan M, Boyle DL, Chabaud-Riou M, Hammaker D, Firestein GS. Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK. Arthritis Rheum. 2003 Sep; 48(9):2450-60.
  29. Shimodaira H, Yoshioka-Yamashita A, Kolodner RD, Wang JY. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc Natl Acad Sci U S A. 2003; 100(5):2420-2425.
  30. Zhang P, Bhakta K, Purl PL, Newbury R, Feramisco J, Wang J. Association of ATM Gene Mutation/Deletion with Rhabdomyosarcoma. Cancer Biol Ther 2:87-91, 2003.
  31. Kawamura S, Miyamoto S, Brown JH. Initiation and transduction of stretch-induced Rho and Rac1 activation through caveolae. J Biol Chem. 278(33):31111-31117, 2003.
  32. Gambello MJ, Darling DL, Yingling J, Tanaka T, Gleeson JG, Wynshaw-Boris A. Multiple dose-dependent effects of Lis1 on cerebral cortical development. J Neurosci. 2003 Mar 1;23(5):1719-29.
  33. Chung H-H, Harms G, Seong CM, Choi B, Min C, Taulane JP, Goodman M. Dendritic Oligo-Guanidines as Molecular Translocators for Intracellular Delivery. Peptide Science, Vol. 76,000-000 (2004).
  34. Dewji N, Valdez D and Singer SJ. The presenilins turned inside out: Implications for their structures and functions. PNAS 101:1057-1062, 2004.
  35. Goodyear C, Narita M, and Silverman GJ. In vivo VL targeted activation-induced apoptotic supra-clonal deletion by a microbial B-cell toxin. J. Immunol. 2004, In press.
  36. Tanaka T, Serneo F, Tseng H, Kulkarni AB, Tsai L-H, Gleeson J. Cdk5 phosphorylation of doublecortin regulates its effect on neuronal migration. Neuron, in press.
  37. Higginbotham H, Bielas S, Tanaka T, Gleeson JG. Transgenic mouse line with
  38. Green-fluorescent protein-labeled Centrin 2 allows visualization of the centrosome in living cells. Transgenic Research in press
  39. Tanaka T, Serneo, FF, Paczkowski C, Gambello MJ, Wynshaw-Boris A, Gleeson JG. Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration. J Cell Biol. In Press.
  40. Wei G, Bai X, and Esko JD. (2003) Temperature-sensitive glycosaminoglycan biosynthesis in a Chinese hamster ovary cell mutant containing a point mutation in glucuronyltransferase I. J. Biol. Chem., in press.
  41. Roth DM, Lai NC, Gao MH, Drumm JD, Jimenez J, Feramisco JR, Hammond HK. Indirect Intracoronary Delivery of Adenovirus Encoding Adenylyl Cyclase Increases Left Ventricular Contractile Function in Mice. A J Physiol Heart Circ Physiol., in press, 2004.
  42. Hammaker D, DL Boyle, MM Chabaud-Riou, and GS Firestein. Regulation of JNK by MEKK2 and MAP kinase kinase kinases in rheumatoid arthritis. J Immunol, in press.
  43. Pecot MY, Malhotra V. Golgi membranes remain segregated from the endoplasmic reticulum during mitosis in mammalian cells. Cell 116(1): 99-107, 2004.
  44. Johnson E, Seasholtz T, Brown JH, Druey KM. RGS16 inhibits signaling through the Galph13-Rho axis. Nature Cell Biology. 2003 Dec; 5: 1095-103. Epub 2003, in process.