Biorepository
Leader
Richard B. Schwab MD
rschwab@ucsd.edu
Contact
Email: ccbr@ad.ucsd.edu
Service Profile
The Biorepository contains plasma, serum, RNA stabilized buffy coat, urine, viable tumor samples, and formalin-fixed paraffin-embedded tumor; all with associated clinical information. These can be provided to investigators with Cancer Sample Banking Committee approval (IRB approval is also required for projects requesting ongoing sample collection or clinical annotation.) Urine and blood-derived specimens are available from a wide variety of cancer cases and cancer-free controls. Tumor sample availability is more limited and predominately from breast and gastrointestinal malignancies. Samples are collected from consented subjects and de-identified clinical information on the subjects is collected over time. Subjects are consented for research germ line genotyping. Access to the clinical annotation is determined based on need as justified in each investigator's request or protocol.
Anonymized samples from the biorepository are available compliant with UC San Diego HRPP exempt category 4. For this sample type submit a brief request (including scientific rationale and required clinical annotation) to ccbr@ad.ucsd.edu.
For projects requiring ongoing sample collection or clinical annotation please complete an IRB protocol and submit this to ccbr@ad.ucsd.edu for review by the Cancer Sample Banking Committee. Once approved, the same protocol can then be submitted for IRB approval. The following boilerplate protocol is provided as a courtesy; due to the changing requirements for human subjects research modifications may be requested during review.
Biorepository Specimen Use Protocol - Boilerplates
Anonymous clinical characteristics of our subjects and the types of samples available can now be searched through the NCI's Early Detection Research Network, Research Network Exchange (ERNE) at the following site.
https://ginger.fhcrc.org/edrn/imp/GateServlet