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CANCER FACTS - Breast

Signs and Symptoms The earliest sign of breast cancer is usually an abnormality that shows up on a mammogram before it can be felt by the woman or her health care provider. When breast cancer has grown to the point where physical signs and symptoms exist, these may include a breast lump, thickening, swelling, distortion, or tenderness; skin irritation or dimpling; and nipple pain, scaliness, or retraction. Breast pain is very commonly due to benign conditions and is not usually the first symptom of breast cancer.
Risk Factors

The risk of breast cancer increases with age. The risk is higher in women who have a personal or family history of breast cancer, biopsy-confirmed atypical hyperplasia, a long menstrual history (menstrual periods that started early and ended late in life), recent use of oral contraceptives or postmenopausal estrogens and who have never had children or had their first child after age 30, consume two or more drinks of alcohol daily, or have higher education and socioeconomic status.

Worldwide, breast cancer incidence rates appear to correlate with variations in diet, especially fat intake, although a causal role for dietary factors has not been firmly established. Additional factors that are currently being studied that may be related to increased or decreased breast cancer risk inclulde: pesticide and other chemical exposures, weight gain, induced abortion, physical inactivity, and selective estrogen-receptor modulators (SERMS) such as tamoxifen and raloxifene.

Exciting new research about BRCAL and BRCA2 susceptibility genes for breast cancer is also in progress, although general screening of the population for these genes is not recommended.

Early Detection Mammography is especially valuable as an early diagnostic tool because it can identify breast abnormalities that may be cancer at an early stage before physical symptoms develop. Numerous studies have shown that early detection increases survival and treatment options. The large declines in breast cancer mortality have been attributed, in part, to the use of regular screening mammography.

The American Cancer Society recommends that women age 40 and older have an annual mammogram, an annual clinical breast examination by a health care professional, and perform monthly breast self-examination. Women ages 20-39 should have a clinical breast exam performed by a health care professional every three years and should perform monthly breast self-examination.

Most breast lumps are not cancer, but only a physician can make a diagnosis. When a woman has a suspicious lump or when a suspicious area is identified on a mammogram, diagnostic mammography can help determine whether additional tests are needed and if there are other lesions that are too small to be felt in the same or the opposite breast. All suspicious lumps should be biopsied for a definitive diagnosis.

Source: Cancer Facts & Figures 1998 - American Cancer Society

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